Educational Objectives

 Recognize the role of macrophages and lymphocytes
 in atherogenesis.

 Recognize the role of rheology in atherosclerotic coronary
 artery disease.

 Discuss gene transfer in atherogenesis.

 Discuss the pathogenesis of atherosclerosis.

 Discuss the interaction of platelet activation and coagulation
 in atherosclerotic coronary artery disease.

 Recognize the importance of oxidized lipoproteins in atherosclerosis.

 Discuss the microcirculation in atherosclerotic coronary artery disease.
 Recognize the role of cytokines in the regulatory mechanism
 of atherosclerosis.

Subject Content

 Vascular endothelium.

 Role of alterations in the differentiated state of smooth muscle cell
 in atherogenesis.

 The vascular extracellular matrix.

 The pathogenesis of atherosclerosis.

 The role of macrophages.

 The role of the lymphocyte.

 Cytokines and growth regulatory molecules.

 The role of rheology in atherosclerotic coronary artery disease.

 Platelet activation.

 Interaction of platelet activation and coagulation.

 Gene transfer.

 The microcirculation in atherosclerotic coronary artery disease.

 Oxidized lipoproteins and atherosclerosis.

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